A Novel Technology - esCCO

A Novel Technology to Non-Invasively Measure Continuous Cardiac Output from ECG and SpO2

Volumetric Information for All Care Levels
NIHON KOHDEN is redefining Quality of Care with new, non-invasive technologies like PWTT and esCCO™ by introducing volumetric information to all care levels. Since the invention of pulse oximetry by NIHON KOHDEN researcher Takuo Aoyagi in 1974), the pulse wave has become the most commonly used vital signal in clinical practice. The pulse wave can provide time related information such as intravascular pressure transmission as well as information on the volume change of arterial blood. Estimated Continuous Cardiac Output (esCCO) is a new technology to determine the cardiac output using Pulse Wave Transit Time (PWTT) which is obtained by the pulse oximetry and ECG-signals from each cycle of the ECG and peripheral pulse wave. esCCO provides real-time, continuous and non-invasive cardiac output measurement alongside the familiar vital sign parameters of ECG and SpO2.

Principle of esCCO
The possibility to derive the cardiac output from pulse pressure information by, CO = SV × HR = (K × PP) × HR

[CO: cardiac output; SV: stroke volume; K: constant value; PP: pulse pressure; HR: heart rate] established in various continuous cardiac output systems using the pulse-contour-analysis, built the starting point for the novel technology esCCO™. A better correlation between SV and PWTT was observed compared to that between SV and PP), and the formula providing cardiac output values was determined to be expressed by PWTT-Information as follows; CO = SV × HR= K × (α × PWTT + β) × HR = esCCO [α, β: experimental constants]

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PWTT - Pulse Wave Transit Time
Hemodynamic Review Program